ABC News(NEW YORK) -- Ahead of a massive storm system, 10 states are under weather alerts Wednesday morning, with heavy, wet snow falling in the Rockies and flooding expected in the Ohio River Valley.

The storm system Wednesday afternoon is moving into the Gulf Coast and South, with severe storms possible from San Antonio to Houston to parts of Mississippi. Damaging winds, hail and tornadoes are possible. Flooding may stretch north all the way to Louisville.

The storm will move farther east by Thursday afternoon, into the central Gulf Coast region and up closer to the Ohio River Valley. Severe storms may strike anywhere from New Orleans to Tallahassee, Florida.

Heavy rain is expected to strike the East Coast on Friday, stretching from Florida all the way up to the Carolinas and then into the Northeast, where flooding will be possible.

Over the next few days, though, the heaviest rainfalls should be in the Ohio River Valley, where some parts may see half a foot.

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